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17 news posts in Immune system

Featured news

30 Mar 2023

Babies’ gut microbiome not influenced by mothers’ vaginal microbiome composition

By Deborah Pirchner, Frontiers science writer Image: Shutterstock.com Alterations in babies’ gut microbiomes during early life are commonly associated with negative health outcomes later on, including asthma and obesity. Gut microbiome alterations are frequently attributed to how a baby is delivered (birth mode). This gave ground to practices like vaginal seeding, aiming to expose babies born via C-section to their mother’s vaginal microbiome. Canadian researchers have examined this supposed interplay between infant microbiome composition and birth mode and found that mothers’ vaginal microbiome composition does not affect microbiome development of babies. It has been a longstanding assumption that birth mode and associated exposure of newborns to their mothers’ vaginal microbiome during delivery greatly affects the development of babies’ gut microbiome. To test the scientific validity of this assumption, a team of Canadian researchers has now published a study in Frontiers in Cellular and Infection Microbiology in which they examined the effect of maternal vaginal microbiome composition on the development of infants’ stool microbiome at 10 days and three months after birth. “We show that the composition of the maternal vaginal microbiome does not substantially influence the infant stool microbiome in early life,” said Dr Deborah Money, a professor of obstetrics […]

Featured news

11 Oct 2021

Breast milk from Mennonite moms on farms better protects babies from allergies

By Mischa Dijkstra, Frontiers science writer Image credit: Richard L. Bowman / Shutterstock.com A new study is the first to compare breast milk between mothers from the older order Mennonite community who live on traditional farms versus urban women. Communities such as old order Mennonites are known to have a low prevalence of atopic diseases associated with allergies, presumably due to environmental and lifestyle factors. The results show that breast milk from Mennonite mothers is richer in neutral or beneficial bacteria, certain cytokines and fatty acids, and IgA antibodies important for defense against bacteria. Their milk may give babies a better protection against allergens in infancy and later in life. Atopic diseases, which include eczema, allergic rhinitis, asthma, and food allergy, are caused by an innate or acquired allergy to airborne particles, such as pollen, dust, mold, or animal dander, or to foodstuffs like peanut, milk, soy, shellfish, or wheat. Until the early 20th century, allergy was thought to be a rare disease. But since in the 1920s to 1930s and especially since the second half of the 20th century, the prevalence of allergies has exploded in Western societies. For example, the European Academy of Allergy and Clinical Immunology estimates […]

Health

10 Nov 2016

Probiotics improve cognition in Alzheimer’s patients

In a randomized double-blind trial, scientists show for the first time that dietary supplementation with daily dose of probiotic bacteria over a period of just 12 weeks is sufficient to yield a small but significant improvement in the cognitive performance of Alzheimer’s patients. For the first time, scientists have shown that probiotics — beneficial live bacteria and yeasts taken as dietary supplements — can improve cognitive function in humans. In a new clinical trial, scientists show that a daily dose of probiotic Lactobacillus and Bifidobacterium bacteria taken over a period of just 12 weeks is enough to yield a moderate but significant improvement in the score of elderly Alzheimer’s patients on the Mini-Mental State Examination (MMSE) scale, a standard measure of cognitive impairment. Probiotics are known to give partial protection against certain infectious diarrheas, irritable bowel syndrome, inflammatory bowel disease, eczema, allergies, colds, tooth decay, and periodontal disease. But scientists have long hypothesized that probiotics might also boost cognition, as there is continuous two-way communication between the intestinal microflora, the gastrointestinal tract, and the brain through the nervous system, the immune system, and hormones (along the so-called “microbiota-gut-brain axis”). In mice, probiotics have indeed been shown to improve learning and […]